Purexa™ PrA

Protein A Affinity Membrane

 
 

Purexa™ PrA
for Antibody Purification

Our Protein A based affinity membrane chromatography product for capture-step antibody purification. Purexa™ PrA utilizes a convection-based mechanism to improve efficiency, purity, and yield. Download Purexa™ PrA datasheet PDF →

 

Purexa™ PrA DBC 10% versus Speed

  • Loading Buffer: 1xPBS pH 7.3 (15 mS/mL)

  • Sample: 2 mg/mL polyclonal human antibody in Loading Buffer

  • Residence time: 0.6 - 4.8 seconds

 

Purexa™ PrA
Increase Productivity with Purexa

Compared to magnetic and resin beads, Purexa™ PrA affinity membrane chromatography is unaffected by pore diffusion and has no incubation time with overall shorter processing times. Purexa™ PrA can operate at rapid flow rates to enhance productivity while maintaining high purity eluates.

 

Purilogics’ membranes can purify
and are not limited to these common biologics :

The Purexa™ product line has pore sizes ranging from 0.3µm to 5 µm. With a much larger pore size, the target molecule is easily able to bind to the membrane at a high capacity, regardless of the size. Thus, Purilogics’ membrane chromatography products can be applied for the purification of many sizes of biologics while also maintaining and a rapid flow rate and high binding capacity.

 
  • Monoclonal Antibody

  • mRNA

  • Adeno-associated virus (AAV)

  • Lentivirus/Lentiviral vectors (LV)

  • Plasmid DNA

  • Oligo nucleotides; Nucleotides/Nucleosides

Purexa™ membrane series products
Form Factors & Volumes

Purilogics, a Donaldson brand, offers a broad portfolio of Purexa™ membrane series products in various form factors like columns, well plates and cassettes, with membrane volumes as small as 5.5 microliters up to several liters, as well as custom purification solutions.

 

Let’s Chat.

 

Revolutionize your biologics purification process with cutting-edge technology that is easy to plug into existing systems, plan for larger runs and solve your unique bioprocessing challenges.