Purexa™ OdT
mRNA Affinity Membrane
Purexa™ OdT
for mRNA Purification
A rapid mRNA purification product that utilizes affinity membrane adsorber technologies. This chromatography product offers up to 10x the productivity compared to traditional resins. Download Purexa™ OdT datasheet PDF →
How Purexa™ OdT Works
Purexa™ OdT can successfully separate target mRNA species regardless of size. Productivity is enhanced with faster flow rates while providing high purity eluates. Purexa™ OdT paired with our HIC and AEX columns allows for a seamless purification process to isolate mRNA.
Recommended buffers for mRNA purification with Purexa™ OdT
Running Buffer: 50 mM Sodium Phosphate + 250 mM NaCl, pH 7.0
Wash Buffer: 50 mM Sodium Phosphate, pH 7.0
Elution Conditions: Deionized water or 20 mM Tris pH 7.0
Cleaning Solution: 0.1 M NaOH.
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Purexa™ OdT
Increase Productivity with Purexa
As shown in Figures 1-4, Purexa™ OdT membrane chromatography provides high binding capacity and short residual time, regardless of the size of the molecule, resulting in up to 10 times faster processing than with resin chromatography.
Purilogics’ membranes can purify
and are not limited to these common biologics :
The Purexa™ product line has pore sizes ranging from 0.3µm to 5 µm. With a much larger pore size, the target molecule is easily able to bind to the membrane at a high capacity, regardless of the size. Thus, Purilogics’ membrane chromatography products can be applied for the purification of many sizes of biologics while also maintaining and a rapid flow rate and high binding capacity.
Monoclonal Antibody
mRNA
Adeno-associated virus (AAV)
Lentivirus/Lentiviral vectors (LV)
Plasmid DNA
Oligo nucleotides; Nucleotides/Nucleosides
Let’s Chat.
Revolutionize your biologics purification process with cutting-edge technology that is easy to plug into existing systems. Plan for larger runs and solve your unique bioprocessing challenges. Our team of scientists and sales support experts are ready to assist you.
Purexa™ membrane series products
Form Factors & Volumes
Purilogics, a Donaldson brand, offers a broad portfolio of Purexa™ membrane series products in various form factors like columns, well plates and cassettes, with membrane volumes as small as 5.5 microliters up to several liters, as well as custom purification solutions.
