Purilogics’ Jinxiang Zhou recently co-authored an article alongside Camila Leal-Lopes, Sara D’Angelo, Andre A.R. Teixeira, Andrew R.M Bradbury, Fortunato Ferrara, and M. Frank Erasmus – the Head of Bioinformatics at Specifica, Inc. We are excited to announce that this article has been published in the New Biotechnology Journal: High throughput purification of monoclonal recombinant antibodies using a Protein-A coated membrane plate system.

Purilogics offers a wide variety of differentiated products for your purification needs. Here are some highlights on the uniqueness of our membrane chromatography products:..

Fast protein liquid chromatography (FPLC) is a common purification technique used widely in various biologics preparation. Often, we complain how slow chromatography columns are, but we have ignored that FPLC itself can cause more trouble than it is worth.

A key focus of Purilogics is to emphasize the drastic decrease in processing time when using our membranes for biologics purification…

Imagine a glass holding sugar. After adding water, it is left to sit. Ultimately, the sugar will dissolve after a few hours…

At Purilogics, we take pride in designing and developing membrane chromatography technologies for biologics purification. Our mission is to provide rapid and effective purification solutions to help the biopharmaceutical industry simplify biologics purification.

It is quite normal to see low titer recombinant protein feedstreams, such as Fc fusion protein, especially during early stage drug research and discovery. To obtain enough purified recombinant proteins, a large volume of feedstream is usually needed.

Magnetic beads are generally effective to purify antibodies at small scale, but there are quite a few scenarios that they become a detriment to your workflow, such as:…

In antibody sequencing, a small quantity of antibodies with decent purity are needed for subsequent processes. Many antibody sequencing companies also need to provide clients at least milligrams of purified antibody along with sequencing reports.…

Purexa™ PrA mini is designed for rapid processing of small quantity of antibodies, especially at low titers. During elution, the first 0.5 mL was discarded. As is shown in the fitures, a majority of the antibody was eluted in the second 0.5 mL elution fraction, which had a concentration of 3.3 mg/mL and was corresponding to a recovery of 78%.

Host cell proteins (HCPs) refer to a broad spectrum of proteins produced by the cells in which the product of interest is made. HCPs are process related impurities and are one of many critical quality attributes. Both the FDA and EMA require residual HCP to be reduced to an acceptable level.