In vitro-transcribed (IVT) mRNA is an alternative genetic material that can be used in the replacement of plasmid DNA in conventional uses…

Hydrophobic interaction chromatography (HIC) separates molecules based on differences in their hydrophobicity. It is an important technique in both sample analysis and preparative scale purification…

mRNA impurities need to be removed to achieve high potency and safety throughout the production process. mRNA production begins with plasmid DNA, which then needs to be linearized.

Antibody purification often involves the use of resin chromatogra¬phy columns for capture and polishing step purifications. However, pore diffusion of proteins is severely hindered in resins, resulting in low, flow rate-dependent capacity.